Turn off pop-ups on your site. Especially any advertising that pops over and covers the content. It will be viewed as negative
Turn off or change large email pop-ups. They are likely to be penalized
Turn off mobile ads that cover full page
Turn off mobile ads that cover more than 33% of the content
Smaller footer ads (those that stick to the bottom of the screen) are ok.
For information on changes by Google check out - https://www.betterads.org/
And for more info on advertising, get the free ebook - Ads 101 For Bloggers
Best for the New Year!